DOPS 2017 Eye on the future

DOPS 2017 was organized by a collaboration of PhD students between two ophthalmic research centres: Leiden and Nijmegen. DOPS 2017 was entitled: "Eye on the future".


Friday 17th March 2017
8:30 – 9:30: Hotel check-in
9:15 – 09:45: Registration and welcome with coffee and tea
09:45 – 10:00: Opening
10:00 – 11:00: Session 1 oral presentations: "Genetics"
11:00 – 11:20: Coffee break
11:20 – 12:30: Session 2 oral presentations: "Imaging & Basic Science"
12:30 – 13:15: Keynote lecture
13:15 – 14:15: Lunch
14:15 – 14:20: Promotional time
14:20 – 15:15: Poster session
15:15 – 16:00: Keynote lecture
16:00 – 16:20: Coffee break
16:20 – 17:30: Session 3
17:30 – 18:30: Drinks
18:30 – 20:00: Dinner
20:00 – ..:..: Evening program

Saturday 18th March 2017
6:30 – 8:30: Breakfast and check-out
8:45 – 9:00: Welcome with coffee and tea
09:00 – 09:15 Opening
09:15 – 10:10 Poster session
10:10 – 10:30 Coffee break
10:30 – 13:00 Workshop, part 1
13:00 - 14:00 Lunch @ Stoom
14:00 – 14:30 Workshop, part 2
14:30 - 14:35 Award ceremony


DOPS 2017 was held at the Honigcomplex, Nijmegen. Rooms were arranged at the Mercure 4-star Hotel.

Participants DOPS2017

Oral Presentations
Friday, 10:00 - 11:00 Session 1: Genetics
1. Geerlings et al. The functional effect of rare variants in complement genes on C3b degradation in patients with age-related macular degeneration (p. 19)
2. Bonnemaijer et al. Genetics in glaucoma patients of African descent study (GIGA): Genetic African ancestry is associated with central corneal thickness and intraocular pressure in primary open-angle glaucoma patients (p. 20)
3. Kersten et al. Should dry AMD be screened for macular dystrophies prior to inclusion in trials? (p. 21)
4. Schellevis et al. A genetic variant in the NR3C2 gene, encoding the mineralocorticoid receptor,is associated with chronic central serous choroiretinopathy (p. 22)
5. Peynshaert et al. Toward rational design of gene carriers: a novel ex vivo model to study the vitreoretinal interface as a barrier (p. 23)

Friday, 11:20 - 12:30 Session 2: Imaging & Basic science
1. Van Vugt et al. Personalized eye-models for optical assessment of ocular conditions (p. 24)
2. De Breuk et al. Three distinctive vascular plexuses in Macular Telangiectasia type 2 using optical coherence tomography angiography (p. 25)
3. Venhuizen et al. Fully automated detection of hyperreflective foci in optical coherence tomography (p. 26)
4. Habeeb et al. The effect of cortisol on human choroidal endothelial cells: a model to study central serous chorioretinopathy (p. 27)
5. Van den Bogerd et al. The lens capsule as a scaffold for corneal endothelial tissue engineering (p. 28)
6. Verhagen et al. Metabolic signature of the aqueous humor distinguishes patients with HLA-B27 associated anterior uveitis from idiopathic anterior uveitis (p. 29)

Friday, 16:20 - 17:30 Session 3: Clinical ophthalmology
1. Wierenga et al. Tumor pigmentation in uveal melanoma is related to eye color (p. 30)
2. Ismalaj et al. The occurence of diplopia and its correlation with motility changes (p. 31)
3. Laban et al. Orbital lymphomas missed by first biopsies of orbital masses (p. 32)
4. Trzcionkowska et al. Outcomes of treatment for retinopathy of prematurity from three university hospitals in a Dutch national inventory (2010-2016) (p. 33)
5. Risseeuw et al. Visual impairment in 188 patients with pseudoxanthoma elasticum (p. 34)
6. Brouwer et al. Treatment of conjunctival melanoma in a Dutch referral center (p. 35)

Poster Presentation

1. Mohabati et al. Severe phenotypes of chronic central serous retinopathy: clinical characteristics and response to photodynamic theraphy (p. 38)
2. Tedja et al. Elucidating pathophysiological pathways and regulators of refractive error (p. 39)
3. Woutersen et al. Perceptual and cognitive functions involved in the useful field of view (p. 40)
4. Devoldere et al. mRNA to induce sustained expression of neurotrophic factors in the retina (p. 41)
5. Valkenburg et al. Differentatial progression of Stargardt disease between young infancy and late adulthood (p. 42)
6. Van Rijssen et al. Redifining optical coherence tomography parameters and treatment outcome in chronic central serous chorioretinopathy treated with half-dose photodynamic
therapy (p. 43)
7. Vroemen et al. “Under pressure”: an in vitro glaucoma model for retinal ganglion cells (p. 44)
8. Brouwer et al. Electroretinogram abnormalities in uveitis in childhood (p. 45)
9. Colijn et al. Progression time to foveal loss in geographic atrophy (p. 46)
10. Martens et al. Persistent postoperative cystoid macular edema after vitreo-retinal surgery
(p. 47)
11. Smid et al. Depth localization and treatment follow-up of a juxtapapillary retinal capillary hemangioma with optical coherence tomography angiography: a case report (p. 48)
12. Talib et al. RPGR-associated retinal dystrophies: a longitudinal study (p. 49)
13. Zhang et al. A new Raman spectrometer device for non-invasive determination of the molecular composition of the living eye (p. 50)
14. Wing et al. Neovascular age-related macular degeneration without drusen in the fellow eye: clinical spectrum and therapeutic outcome (p. 51)
15. Louer et al. The role of SUCNR1 in age-related macular degeneration (p. 52)
16. Hubens et al. A new Raman spectrometer device for non-invasive determination of the molecular composition of the living eye (p. 53)


Academic Hospital Maastricht: 9
Bartiméus: 2
Erasmus University Medical Center: 7
Leiden University Medical Center: 9
Radboud university medical center: 23
Rotterdam Eye Hospital: 3
University Hospital Antwerp: 2
University Hospital Brussels: 1
University Medical Center Groningen: 5
University Medical Center Utrecht: 5

DOPS 2016 Organizing Committee

Eveline Kersten

Radboud University Medical Center

DOPS2016 President

The main focus of my project is to identify risk factors and biomarkers for progression in the dry form of age-related macular degeneration (AMD). To date, no curative treatment is available for dry AMD. If we know the factors contributing to development and progression of AMD, we can better predict which patients are most likely to suffer from advanced AMD and moreover new treatments can be developed and evaluated in the future.
Hobbies: Badminton, reading and dining

Roos Schellevis

Radboud University Medical Center

DOPS2016 Treasurer

During my PhD project I am trying to elucidate the genetics of chronic central serous chorioretinopathy (cCSC). Although we still do not know the exact cause of the disease, it has been associated to corticosteroid use, the male gender and stress. Using various genotyping methods we hope to understand the biological mechanism behind cCSC, with the aim to improve patient’ treatment.

Hobbies: Hobbies: Volleyball, reading, (board)games, mountainbike riding


Soraya Jonker

University Eye Clinic Maastricht, MUMC+

DOPS 2016 Secretary

Spectacle independence is a much desired outcome in patients undergoing cataract or refractive surgery. My research focuses on intraocular lenses (IOLs) for the correction of refractive errors in pseudophakic and phakic patients. Currently, we are studying new types of multifocal IOLs in pseudophakic patients as well as the long term effects of iris-fixated IOLs in phakic patients.

Hobbies: Hobbies: yoga, interior design, reading, dining

Natalia Makhotkina

University Eye Clinic Maastricht

DOPS 2016 Public relations

Cataract surgery is one of the most common surgical procedures worldwide and is also an intervention with a highly predictable outcome. However, some patients may be dissatisfied with their vision, despite excellent surgical results and good visual acuity. We are investigating factors which may contribute to the different perception of the quality of vision and predispose some patient to development of visual complaints, such as halo’s, glare, shadows and ghosting after implantation of monofocal and multifocal intraocular lenses.
Hobbies: Hobbies: dancing, playing piano and reading